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History of Psychiatry
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Infectious insanities, surgical solutions: Bayard Taylor Holmes, dementia praecox and laboratory science in early 20th-century America. Part 2

Richard Noll

Psychology Department, DeSales University, Center Valley, PA 18034-9568, USA; Richard.Noll{at}desales.edu

Part I of this article on Bayard Taylor Holmes (1852–1924), a Chicago physician and surgeon, detailed his laboratory research on dementia praecox and his presumed discovery in 1915 of evidence in support of a focal infection theory of its aetiology. In May 1916 he began to experiment with a rational therapy based on this theory: abdominal surgery and daily irrigations of the colon. He operated first on his own son, who had been afflicted with dementia praecox since 1905, but he died four days later. Part II deals with Holmes' continued surgical treatment of dementia praecox patients and the outcomes of the operations. It also describes how Holmes set up the short-lived Psychiatric Research Laboratory of the Psychopathic Hospital at Cook County Hospital in 1917, and discusses the dismissal of a key research colleague, H. M. Jones, whose experimental results directly contradicted those of Holmes.

Key Words: autointoxication theory in psychiatry • Bayard Taylor Holmes • dementia praecox • focal infection theory in psychiatry • surgical treatments in psychiatry

History of Psychiatry, Vol. 17, No. 3, 299-311 (2006)
DOI: 10.1177/0957154X06059446


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This article has been cited by other articles:


Home page
History of PsychiatryHome page
R. Noll
Kraepelin's 'lost biological psychiatry'? Autointoxication, organotherapy and surgery for dementia praecox.
History of Psychiatry, September 1, 2007; 18(71 Pt 3): 301 - 320.
[Abstract] [PDF]


Home page
History of PsychiatryHome page
R. Noll
The blood of the insane.
History of Psychiatry, December 1, 2006; 17(68 Pt 4): 395 - 418.
[Abstract] [PDF]